Alloplex Biotherapeutics

Alloplex Biotherapeutics

Private
Woburn, MassachusettsHealthcare & Life Scienceshttps://alloplexbio.com/

Last Round

Series A

Feb 9, 2023

Total Funding Raised

$21.7M

Company Overview

Alloplex Biotherapeutics, Inc. is a privately held, clinical-stage biotechnology company founded in 2016 with headquarters in Woburn, Massachusetts. The company focuses on developing cellular therapies for cancer treatment. Its proprietary ENLIST platform is used to create SUPLEXA, a non-engineered, autologous cellular therapy derived from a patient's own peripheral blood mononuclear cells. This therapy involves activating the patient's immune cells in a lab to enhance their natural cancer-fighting abilities before reintroducing them to the patient. Alloplex has completed a Phase I clinical trial in Australia, which demonstrated a strong safety profile and clinical activity in patients with solid tumors, including complete and partial responses in end-stage colorectal cancer patients. The company is planning to submit an Investigational New Drug (IND) application to the FDA and initiate Phase II trials in 2025, exploring SUPLEXA in combination with immune checkpoint inhibitors. Alloplex is actively seeking strategic partnerships and further investment to advance its clinical programs.

Sector

Healthcare & Life Sciences

Verticals

Biotechnology, Clinical Trials, Precision Medicine, Drug Discovery

Business Model

B2B

Customer Profile

Services & Consulting, Government Contracts

AI Layer

Non-AI

Keywords

autologous cell therapynon-engineered cell therapycell therapycancer immunotherapyadoptive cell therapyACTsolid tumor treatmentex-vivo cell activationimmune cell trainingpolyclonal cell therapyCAR-T alternativePBMCsclinical-stage biotechcolorectal cancerrenal cell carcinoma

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Alloplex Biotherapeutics Comps

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CompanyStatusEst. ValuationRev Multiple
OpenAIPrivate$86.0B~40x
CoherePrivate$5.0B--
Competitor 1Public$XX.XBXXx
Competitor 2Public$XX.XBXXx

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Alloplex Biotherapeutics Funding Rounds

Historical fundraising activity

RoundDateAmount RaisedValuationInvestorsSources
Series AFeb 9, 2023
SeedAug 19, 2021

Key People

Founding team and executive leadership

Frank Borriello

CEO

Executive Team

Alloplex Biotherapeutics Investors

Notable investors and investment history

InvestorRounds
The Wells InvestmentSeries A
Keiretsu ForumSeries A

Alloplex Biotherapeutics Filings

SEC and related filings with document metadata.

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Alloplex Biotherapeutics Filings

SEC and related filings with document metadata.

Frequently Asked Questions

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Firmographic Details

HeadquartersWoburn, Massachusetts
Employee Range5
Year Founded2016
Last FundingFeb 9, 2023

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