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Denali Therapeutics

Denali Therapeutics

Public
South San Francisco, CaliforniaBiotechhttps://www.denalitherapeutics.com/

Denali Therapeutics is now publicly traded

The data on this page reflects Denali Therapeutics's private-market history up to the point it went public, including its funding rounds, valuation, and investors.

Went Public

Dec 7, 2017

Last Round

Follow-on Offering

Dec 10, 2025

Total Funding Raised

$1.61B

Company Overview

Denali Therapeutics is a biotechnology company that discovers and develops innovative biotherapeutics designed to cross the blood-brain barrier for the treatment of neurodegenerative and lysosomal storage diseases.

Sector

Biotech

AI Layer

Non-AI

Keywords

biopharmaceuticalblood-brain barrierneurodegenerative diseasedrug delivery platformtransport vehicle technologyTV platformBBB deliveryCNS therapeuticsbiotech pipelineenzyme replacement therapykinase inhibitorclinical-stage biotechlysosomal storage diseasedrug licensingbiotech pharma partner

Denali Therapeutics Comparables

Compare Denali Therapeutics with similar companies based on industry and business-model similarity.

Denali Therapeutics comparables — related companies by embedding similarity
CompanySimilarityMarket Cap
Atacama Therapeutics, Inc.
63%
Anacalypsis Therapeutics
59%
Kurve Therapeutics, Inc.
59%
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Denali Therapeutics Funding Rounds

Historical fundraising activity

Data table
RoundDateAmount RaisedValuationInvestorsSources
Follow-on OfferingDec 10, 2025
StrategicDec 4, 2025
PIPEFeb 27, 2024
IPODec 7, 2017
Series BAug 25, 2016
Series A
May 14, 2015
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Key People

Founding team and executive leadership

Ryan Watts

CEO

Executive Team

Alexander Schuth

Chief Operating and Financial Officer

Executive Team

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Denali Therapeutics Investors

Notable investors and investment history

Denali Therapeutics investors
InvestorRounds
Morgan Stanley & Co., LLCFollow-on Offering
F-Prime CapitalSeries B, Series A
Biomatics Capital PartnersSeries A
Morgan StanleyIPO
ARCH Venture PartnersSeries B, Series A
Royalty PharmaStrategic
Goldman Sachs & Co. LLCIPO, Follow-on Offering
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Denali Therapeutics Filings

Explore SEC and related filing metadata, where available.

Denali Therapeutics filings preview — column headings only; records require access
TypeDateAmount OfferedAmount SoldFilingPagesDownload

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Firmographic Details

HeadquartersSouth San Francisco, California
Employee Range565
Year Founded2015
Last FundingDec 10, 2025

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