Fore Biotherapeutics

Fore Biotherapeutics

Private
Philadelphia, PennsylvaniaHealthcare & Life Scienceshttps://fore.bio

Last Round

Series D

Extension

May 22, 2025

Est. Valuation

$75M

Total Funding Raised

$188.5M

Momentum Score

25 /100

Company Overview

Fore Biotherapeutics is a clinical-stage precision oncology company developing treatments for patients with rare, unaddressed tumor mutations. The company utilizes its proprietary functional genomics platform, Foresight, to screen for mutations in cancer-driving genes and identify existing compounds that could be effective therapies. This strategy focuses on in-licensing clinical-stage assets and matching them to hyper-targeted patient populations to accelerate development. The company's lead program is plixorafenib, a next-generation BRAF inhibitor designed to treat a wide range of BRAF-mutated cancers. Originally founded in Israel as NovellusDx, a diagnostics company, it rebranded in 2021 and pivoted to therapeutics, establishing its global headquarters in Philadelphia.

Sector

Healthcare & Life Sciences

Verticals

Biotechnology, Drug Discovery, Precision Medicine, Clinical Trials

Business Model

B2B2C

Customer Profile

Revenue Share

AI Layer

Non-AI

Keywords

precision oncologyBRAF inhibitornext-generation BRAF inhibitorparadox breakerBRAF mutationstargeted cancer therapyoncology therapeuticsdrug developmentclinical-stage biopharmaBRAF fusionssmall-molecule inhibitorgenetically defined cancerdrug in-licensingcentral nervous system tumorsCNS tumorsfunctional genomics

Historical Pricing

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Caplight Momentum Score

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Fore Biotherapeutics Comps

Public and private peers based on sector, stage, and business model.

CompanyStatusEst. ValuationRev Multiple
OpenAIPrivate$86.0B~40x
CoherePrivate$5.0B--
Competitor 1Public$XX.XBXXx
Competitor 2Public$XX.XBXXx

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Fore Biotherapeutics Funding Rounds

Historical fundraising activity

RoundDateAmount RaisedValuationInvestorsSources
Series D ExtensionMay 22, 2025
Series DAug 23, 2023
Series CSep 21, 2020
Series BApr 30, 2018
Series AJun 22, 2016
VC Round
Dec 24, 2015

Key People

Founding team and executive leadership

Michael Byrnes

Chief Financial Officer

Executive Team

Fore Biotherapeutics Investors

Notable investors and investment history

InvestorRounds
3B FUTURE Health FundSeries D, Series D Extension
OrbiMedSeries D, Series B, Series C, Series A, Series D Extension
Novartis Venture FundSeries D, Series C, Series D Extension
HBM Healthcare InvestmentsSeries D, Series C, Series D Extension
Wellington ManagementSeries D, Series C, Series D Extension
Takeda VenturesSeries C
SR OneSeries C, Series D, Series D Extension

Market signals

Structured signals derived from secondary market and firmographic data.

  • Nov 15, 2025

    Preparing for registration and launch of plixorafenib for BRAF mutations.

  • May 22, 2025

    $38M raised in Series D Extension round.

Fore Biotherapeutics Filings

SEC and related filings with document metadata.

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Fore Biotherapeutics Filings

SEC and related filings with document metadata.

Frequently Asked Questions

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Firmographic Details

HeadquartersPhiladelphia, Pennsylvania
Employee Range56
Year Founded2011
Last FundingMay 22, 2025

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