NRG Therapeutics

NRG Therapeutics

Private
Stevenage, EnglandHealthcare & Life Scienceshttps://www.nrgtherapeutics.com

Last Round

Series B

Sep 8, 2025

Total Funding Raised

$95.4M

Company Overview

NRG Therapeutics is a neuroscience-focused drug discovery company developing treatments for neurodegenerative disorders such as Parkinson's disease and Amyotrophic Lateral Sclerosis (ALS). The company's approach is centered on leveraging breakthrough science in mitochondrial biology to create first-in-class, brain-penetrant, oral small molecule inhibitors of the mitochondrial permeability transition pore (mPTP). By inhibiting the mPTP, NRG aims to restore mitochondrial function, protect neurons, reduce neuroinflammation, and ultimately slow or halt the progression of these diseases. Founded in 2018, the company is backed by a syndicate of venture capital investors and has received grant funding from organizations like The Michael J. Fox Foundation. Its lead candidate, NRG5051, has completed pre-clinical studies and is expected to enter clinical trials in early 2026.

Sector

Healthcare & Life Sciences

Verticals

Drug Discovery, Biotechnology, Clinical Trials

Business Model

B2B

Customer Profile

Revenue Share, Government Contracts

AI Layer

Non-AI

Keywords

mPTP inhibitorsneurodegenerative diseasessmall molecule drugsParkinson's diseaseALSmitochondrial permeability transition poremPTPmotor neurone diseaseMNDdrug discoverydisease-modifying therapymitochondrial dysfunctionbrain-penetrant drugsneuroinflammationpre-clinical biotech

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NRG Therapeutics Comps

Public and private peers based on sector, stage, and business model.

CompanyStatusEst. ValuationRev Multiple
OpenAIPrivate$86.0B~40x
CoherePrivate$5.0B--
Competitor 1Public$XX.XBXXx
Competitor 2Public$XX.XBXXx

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NRG Therapeutics Funding Rounds

Historical fundraising activity

RoundDateAmount RaisedValuationInvestorsSources
Series BSep 8, 2025
GrantOct 31, 2024
GrantSep 5, 2024
GrantFeb 22, 2023
Series ANov 9, 2022
Grant
May 30, 2022

Key People

Founding team and executive leadership

Neil Miller

Co-Founder And CEO

Founding Team

NRG Therapeutics Investors

Notable investors and investment history

InvestorRounds
Innovate UKGrant
Omega FundsSeries B, Series A
SV Health InvestorsSeries B
Criteria Bio VenturesSeries B
Parkinson's UKSeries A, Seed, Series B
M VenturesSeries B
British Business BankSeries B

Market signals

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  • Oct 23, 2025

    Kathryn Oliver appointed to newly created role.

  • Oct 23, 2025

    David Brocklebank appointed to newly created role.

NRG Therapeutics Filings

SEC and related filings with document metadata.

TypedDateAmount OfferedAmount SoldFillingPagesDownload
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NRG Therapeutics Filings

SEC and related filings with document metadata.

Frequently Asked Questions

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Firmographic Details

HeadquartersStevenage, England
Employee Range21
Year Founded2018
Last FundingSep 8, 2025

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