Pretzel

Pretzel

Private
Waltham, MassachusettsHealthcare & Life Scienceswww.pretzeltx.com

Last Round

VC Round

Jul 14, 2025

Total Funding Raised

$72.5M

Momentum Score

25 /100

Company Overview

Pretzel Therapeutics is a biotechnology company focused on developing therapies to reverse mitochondrial dysfunction by utilizing a comprehensive understanding of mitochondrial biology to address the underlying causes of common diseases, including age-related disorders.

Sector

Healthcare & Life Sciences

Verticals

Drug Discovery, Biotechnology, Precision Medicine, Clinical Trials

Business Model

B2B

Customer Profile

Revenue Share, Government Contracts

AI Layer

Non-AI

Keywords

mitochondrial therapiesmitochondrial dysfunctionPOLG therapiesrare disease therapymitochondrial DNA depletion syndromesMDDSgene editingsmall molecule drugsclinical stage biotechaging-related diseasesPOLGmitochondrial gene editinggene expression modulationmitochondrial quality controlbioenergetics restoration

Historical Pricing

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Caplight Momentum Score

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Pretzel Comps

Public and private peers based on sector, stage, and business model.

CompanyStatusEst. ValuationRev Multiple
OpenAIPrivate$86.0B~40x
CoherePrivate$5.0B--
Competitor 1Public$XX.XBXXx
Competitor 2Public$XX.XBXXx

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Pretzel Funding Rounds

Historical fundraising activity

RoundDateAmount RaisedValuationInvestorsSources
VC RoundJul 14, 2025
Series ASep 12, 2022

Key People

Founding team and executive leadership

Jay Parrish

Chairman And CEO

Executive Team

Baruch Harris

Chief Operating Officer

Executive Team

Pretzel Investors

Notable investors and investment history

InvestorRounds
Vasa Angels ISeries A
GVSeries A
HealthCapSeries A
Eir VenturesSeries A
ARCH Venture PartnersSeries A
Cambridge EnterpriseSeries A
Mubadala CapitalSeries A

Market signals

Structured signals derived from secondary market and firmographic data.

  • Mar 11, 2026

    PX578 data presented at the 2026 MDA Clinical & Scientific Conference.

  • Mar 11, 2026

    Presented data at the 2026 MDA Clinical & Scientific Conference.

Pretzel Filings

SEC and related filings with document metadata.

TypedDateAmount OfferedAmount SoldFillingPagesDownload
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Pretzel Filings

SEC and related filings with document metadata.

Frequently Asked Questions

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Firmographic Details

HeadquartersWaltham, Massachusetts
Employee Range47
Year Founded2018
Last FundingJul 14, 2025

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