Profluent Bio

Profluent Bio

Private
Berkeley, CaliforniaHealthcare & Life Scienceshttps://www.profluent.bio

Last Round

Early Funding

Nov 19, 2025

Est. Valuation

$1B

Total Funding Raised

$362M

Momentum Score

75 /100

Company Overview

Profluent is a biotechnology company that develops artificial-based proteins by integrating real-world wet lab characterization with advanced generative AI models to enhance biomolecule research for human health and industrial applications.

Sector

Healthcare & Life Sciences

Verticals

Biotechnology, Drug Discovery, Medical AI

Business Model

B2B

Customer Profile

Services & Consulting, Revenue Share

AI Layer

Infrastructure

Keywords

AI protein designgenerative protein designgene editingcustom gene editorsprogrammable biologyfrontier AI modelslarge language modelsCRISPRAI biotechgenetic medicinesOpenCRISPRprotein engineeringwet-lab validationdiscovery partnershipsbase editors

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Caplight Momentum Score

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Profluent Bio Comps

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CompanyStatusEst. ValuationRev Multiple
OpenAIPrivate$86.0B~40x
CoherePrivate$5.0B--
Competitor 1Public$XX.XBXXx
Competitor 2Public$XX.XBXXx

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Profluent Bio Funding Rounds

Historical fundraising activity

RoundDateAmount RaisedValuationInvestorsSources
Early FundingNov 19, 2025
Series BNov 19, 2025
Series BMay 22, 2024
Series AMar 21, 2024
SeedJan 26, 2023

Profluent Bio Investors

Notable investors and investment history

InvestorRounds
Air Street CapitalSeries B, Early Funding, Seed, Series A
Bezos ExpeditionsSeries B, Early Funding
Convergent VenturesSeed
Spark CapitalSeries B, Early Funding, Series A
AIX VenturesSeed
Insight PartnersSeries B, Early Funding, Series A, Seed
Altimeter Capital ManagementSeries B

Market signals

Structured signals derived from secondary market and firmographic data.

  • Apr 28, 2026

    Multi-program deal worth up to $2.25 billion for AI-designed enzymes.

  • Nov 19, 2025

    $106M round raised

Profluent Bio Filings

SEC and related filings with document metadata.

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Profluent Bio Filings

SEC and related filings with document metadata.

Frequently Asked Questions

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Firmographic Details

HeadquartersBerkeley, California
Employee Range53
Year Founded2022
Last FundingNov 19, 2025

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