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ARPA-H

ARPA-H

District of Columbiaarpa-h.gov

Overview

A U.S. government research funding agency within the Department of Health and Human Services (HHS) that supports transformative, high-risk, high-reward biomedical and health research. Modeled after the Defense Advanced Research Projects Agency (DARPA), it was established to accelerate breakthroughs in medicine and health that cannot be readily accomplished through traditional research or commercial activity. ARPA-H is disease-agnostic and funds projects using mechanisms like cooperative agreements and Other Transaction Authority (OTA) agreements, rather than providing dilutive capital. It operates as an independent entity within the National Institutes of Health (NIH).

Portfolio Companies

46

Website

arpa-h.gov

Investments

ARPA-H investments
CompanyDateStageLead
GEMMA BiotherapeuticsJul 2026GrantCo-investor
Ksana HealthMay 2026GrantCo-investor
Diamond TherapeuticsMay 2026GrantCo-investor
Esperto MedicalApr 2026GrantCo-investor
Duracyte Inc.Apr 2026GrantCo-investor

Key People

Maryam Ziaei

Director of Technology Transfer and Transition (T3X)

Sector & Stage Mix

Industry, funding stage, and valuation band breakdowns.

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SeedSeries ASeries BGrowth

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Investment Activity

Yearly cadence, pace, and funding raised over time.

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2021
2022
2023
2024
2025
2026

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FAQ

Firmographic Details

HeadquartersDistrict of Columbia
Year FoundedN/A

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