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Palo Santo

Palo Santo

Chicago, Illinoispalosanto.com

Overview

Palo Santo is a venture capital fund focused on emerging psychedelic medicines and therapies poised to address the growing mental health crisis and creating a new paradigm in wellbeing . The fund targets a diverse range of companies offering innovative solutions across biopharma, drug development, digital therapeutics, healthcare services and tech-enabled solutions to address the growing global mental health crisis . From cutting-edge science to commercial application, Palo Santo's portfolio includes 20+ companies focused on advancing the field of psychedelic medicines and expanding patient access and affordability .

Year Founded

2020

AUM

$50M

Portfolio Companies

8

Investments

Palo Santo investments
CompanyDateStageLead
Syndeio BiosciencesMay 2025VC RoundCo-investor
Xylo BioJun 2024SeedCo-investor
Journey ClinicalJan 2023Series ACo-investor
Sensorium TherapeuticsNov 2022Series ACo-investor
FluenceFeb 2022SeedLead

Sector & Stage Mix

Industry, funding stage, and valuation band breakdowns.

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SeedSeries ASeries BGrowth

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Investment Activity

Yearly cadence, pace, and funding raised over time.

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2021
2022
2023
2024
2025
2026

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Firmographic Details

HeadquartersChicago, Illinois
Year Founded2020
AUM$50M

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