TwentyTwo VC
San Francisco, Californiatwentytwoventures.com
Overview
An early-stage venture capital firm that invests in ambitious founders building companies in sectors such as SaaS, fintech, open source, marketplaces, and developer tools. The firm has a conviction to invest earlier than most, often before a public launch, and utilizes smaller check sizes to make quick and efficient decisions. It was founded by Katherine Caldwell and has invested in over 100 companies across its first five funds.
Portfolio Companies
15
Website
twentytwoventures.comInvestments
| Company | Date | Stage | Lead |
|---|---|---|---|
| NexStratus | Mar 2026 | Seed | Co-investor |
| UXMagic.ai | Nov 2025 | Series A | Co-investor |
| Dedalus Labs | Oct 2025 | Seed | Co-investor |
| Onyx Bio | Mar 2025 | Seed | Co-investor |
| Pirros | Aug 2023 | Seed | Co-investor |
Key People
Katey Caldwell
Founder and Managing Partner
Sector & Stage Mix
Industry, funding stage, and valuation band breakdowns.
