A-Alpha Bio

A-Alpha Bio

Private
Seattle, WashingtonHealthcare & Life Scienceshttps://www.aalphabio.com/

Last Round

Grant

May 21, 2024

Total Funding Raised

$65.1M

Company Overview

A-Alpha Bio is a biotechnology company that combines synthetic biology and machine learning to analyze protein-protein interactions for drug discovery and development. The company was founded in 2017 as a spinout from the University of Washington's Institute for Protein Design. A-Alpha Bio has two main platforms: AlphaSeq, which experimentally measures millions of protein-protein interactions simultaneously, and AlphaBind, a machine learning platform trained on this data to predict binding from protein sequences. The company leverages these platforms for its internal oncology-focused therapeutic pipeline and through partnerships with major pharmaceutical companies like Bristol Myers Squibb and Gilead Sciences. As of July 2023, A-Alpha Bio had raised a total of $51 million in funding.

Sector

Healthcare & Life Sciences

Verticals

Drug Discovery, Biotechnology, ML Platforms, Medical AI

Business Model

B2B

Customer Profile

Services & Consulting, Revenue Share, Government Contracts

AI Layer

Infrastructure

Keywords

protein-protein interactionsdrug discovery platformPPIsAI drug discoveryhigh-throughput screeningsynthetic biologyprotein binding predictionprotein engineeringantibody discoverymolecular gluesplatform biologyyeast displayprotein interaction datacomputational biologydata flywheelbiologics discoverybiodefense

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A-Alpha Bio Comps

Public and private peers based on sector, stage, and business model.

CompanyStatusEst. ValuationRev Multiple
OpenAIPrivate$86.0B~40x
CoherePrivate$5.0B--
Competitor 1Public$XX.XBXXx
Competitor 2Public$XX.XBXXx

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A-Alpha Bio Funding Rounds

Historical fundraising activity

RoundDateAmount RaisedValuationInvestorsSources
GrantMay 21, 2024
Series A ExtensionJul 25, 2023
GrantMay 16, 2023
GrantMar 1, 2022
Series ASep 8, 2021
Grant
Sep 1, 2020

Key People

Founding team and executive leadership

Randolph Lopez

Co-founder CTO

Founding Team

David Younger

Co-Founder And CEO

Founding Team

A-Alpha Bio Investors

Notable investors and investment history

Market signals

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  • Feb 3, 2026

    Partnered with Novo Nordisk to enhance drug discovery using its AI platform.

  • Sep 23, 2025

    Troy Lionberger appointed to drive next phase of growth.

A-Alpha Bio Filings

SEC and related filings with document metadata.

TypedDateAmount OfferedAmount SoldFillingPagesDownload
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A-Alpha Bio Filings

SEC and related filings with document metadata.

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Firmographic Details

HeadquartersSeattle, Washington
Employee Range50
Year Founded2017
Last FundingMay 21, 2024

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